1. Health
You can opt-out at any time. Please refer to our privacy policy for contact information.

Jarisch-Herxheimer-Like Reaction


Updated March 16, 2008


This reaction is characterized by severe chills, muscle aches, headache, fever, increased heart rate, and increased respiratory rate.

The Jarisch-Herxheimer-like reaction occurs in 14% of patients who are treated for lyme disease. The reaction usually occurs within the first 24 hours of starting antibiotic therapy for lyme disease and lasts for only a few hours. Penicillin and tetracycline cause this reaction more frequently than erythromycin.

Pronunciation: JAIR-ish HIRX-hy-mur • (noun)
  1. About.com
  2. Health
  3. Dermatology
  4. Dermatology Basics
  5. Glossary
  6. J
  7. Jarisch-Herxheimer-Like Reaction

©2014 About.com. All rights reserved.

We comply with the HONcode standard
for trustworthy health
information: verify here.