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Jarisch-Herxheimer-Like Reaction

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Updated March 16, 2008

Definition:

This reaction is characterized by severe chills, muscle aches, headache, fever, increased heart rate, and increased respiratory rate.

The Jarisch-Herxheimer-like reaction occurs in 14% of patients who are treated for lyme disease. The reaction usually occurs within the first 24 hours of starting antibiotic therapy for lyme disease and lasts for only a few hours. Penicillin and tetracycline cause this reaction more frequently than erythromycin.

Pronunciation: JAIR-ish HIRX-hy-mur • (noun)
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