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Epidermis Anatomy

By Heather Brannon, MD, About.com

Updated: September 30, 2007

About.com Health's Disease and Condition content is reviewed by Casey Gallagher, MD

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Epidermis Anatomy - Keratinocyte Maturation

There are four major layers of keratinocytes (the structural cells) in the epidermis and one layer that is present only in certain parts of the body. The bottom layer, the stratum basale, has cells that are shaped like columns. In this layer the cells divide and push already formed cells into higher layers. As cells move into the higher layers, they flatten and eventually die. We will take a closer look at the characteristics of each of these layers.

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