By Heather Brannon, MD, About.com
Created: August 25, 2006
About.com Health's Disease and Condition content is reviewed by Casey Gallagher, MD
Generalized vaccinia consists of vesiclesor pustulesthat appear on normal skin away from the vaccination site. It is believed that this condition is caused by the spread of the virus in the bloodstream, not direct contact. Prior to 1960, this occurred in 242 people per 1 million people vaccinated.
Smallpox - The DiseaseThe History of SmallpoxThe Smallpox Vaccine
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