Treatment of Squamous Cell Carcinoma
Treatment options for this skin cancer depend on information gleaned from the biopsy.
Electrodessication and curettage - This procedure involves destroying the skin cancer with an electrocautery device then scraping the area with a curet. Many times the diseased tissue can be differentiated from the normal tissue by the texture felt while scraping. This process is repeated several times to ensure complete removal of the skin cancer. This procedure is useful for small tumors 1 cm or less in diameter on the neck, trunk, arms, or legs. However, it tends to leave a scar.
Simple excision - This procedure involves surgical excision of the skin cancer including a margin of normal skin. For tumors of 2 cm or less, a margin of 4 mm is sufficient; for tumors >2 cm, the best margin is 6 mm. The advantage of this treatment is that it is quick and inexpensive. However, the difference between normal and cancerous tissue must be judged with the naked eye.
Mohs' micrographic surgery - This procedure is must be performed by an experienced Mohs' surgeon. It involves excision of the skin cancer and immediate examination of the tissue under the microscope to determine margins. If any residual skin cancer is left, it can be mapped out and excised immediately. The process of excision and examination of margins may have to be repeated several times. The advantage of this technique is that it is usually definitive and has been reported to have a lower recurrence rate than other treatment options. The disadvantage is the time and expense involved.
Radiation therapy - This procedure involves a course of radiation therapy to the tumor area. At this time, however, there is insufficient evidence that radiation after surgery improves the recurrence rate of squamous cell carcinoma. It can also have the long-term effects of scarring, ulceration, and thinning of the skin.
Chemotherapy - The type of chemotherapy used is 13-cis-Retinoic acid and interferon-2A. Chemotherapy is used for advanced stages of squamous cell carcinoma.
Cryotherapy - This procedure involves destroying the tissue by freezing it with liquid nitrogen. This may be effective for small, well-defined superficial skin cancers. It is also used effectively for the treatment of actinic keratosis, a premalignant condition. This procedure is inexpensive and time-efficient but can only be used in a small number of cases.
Prevention of Squamous Cell Carcinoma
Avoid UVB radiation from sun exposure - Avoid midday sun, use protective clothing, and use sunscreen with an SPF of at least 15. This is especially important for children.
Avoid tobacco products - This includes cigars, cigarettes, chewing tobacco, and snuff. Since these products increase the risk squamous cell carcinoma on lip and mouth, their use should be reduced or cut out altogether.
Avoid polycyclic hydrocarbons - Jobs that require contact with these compounds are highly regulated. Use protective gear at all times while working with these compounds.
Have suspicious lesions checked out - If you have a question, get it checked out. Treating premalignant lesions prevents their transformation to potentially metastatic skin cancer.
