In a new study published in the Journal of Biological Chemistry, researchers describe the possibility that turning on a certain gene could prevent skin cancer.
One type of skin cancer, squamous cell carcinoma, starts on the top layer of the skin. Exposure to UV radiation can damage the DNA of a skin cell. A protein called protein kinase C (PKC) repairs the DNA damage and if there is too much damage, PKC tells the cell to die.
One part of cell division involves splitting DNA in half and copying the other side. There are checkpoints along the way where the cell repairs any damage to the DNA before going on. This study found that the PKC gene is responsible for stopping at these checkpoints, but in squamous cell carcinoma, the PKC gene is turned off.
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